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Which scans should be excluded from a run depends on which analysis method is used. Some whole boundary methods provide enough accuracy that even data that has not cleared the meniscus or data that doesn't exhibit a stable plateau can be included in the analysis. Methods for which this is true include the finite-element method and some approximated solutions to the Lamm equation that model the boundary conditions accurately enough with error functions. For more information, see Demeler et al, Biophys. J., 1998.
Please note that you can still exclude scans later when you perform an analysis that cannot accommodate scans too close to the meniscus or without a stable plateau. Therefore, it may be better to leave all available scans in the dataset at this point since they may be useful to increase the fitting confidence for some boundary methods.
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Last modified on January 12, 2003.